Abdominal angina that is characterized by postprandial pain, and often
associated with weight loss, is a well-recognized symptom complex of
mesenteric artery insufficiency (mesenteric territory symptoms). In th
e past 5 years, we have observed six patients with atypical symptoms w
ho had mesenteric artery occlusion combined with stenosis or occlusion
of the celiac artery. Atypical symptoms included severe nausea and vo
miting at the sight or smell of food, anorexia, weight loss, and right
upper quadrant or epigastric discomfort (celiac territory symptoms).
An extensive work-up to rule out gastric, pancreatic, biliary, or colo
nic pathology was undertaken in these patients. The findings included
gallbladder dysfunction, diffuse micro-ulceration of gastric mucosa, a
nd colonic mucosal ulceration. The diagnosis of visceral artery occlus
ion was initially missed in all six patients. Four patients had cholec
ystectomy. Visceral angiography confirmed occlusion of the celiac, sup
erior, and inferior mesenteric arteries. Five patients had dramatic re
solution of symptoms after restoration of visceral circulation. One pa
tient who developed intestinal infarction before revascularization die
d. Symptoms suggesting upper abdominal visceral pathology may be a man
ifestation of celiac artery stenosis/occlusion coexisting with mesente
ric artery occlusive disease. Visceral angiography should be part of t
he work-up in these patients for early diagnosis and prompt management
.