THE ANTICONVULSANT HYPERSENSITIVITY SYNDROME

Authors
HANDFIELDJONES SE JENKINS RE WHITTAKER SJ BESSE CP MCGIBBON DH
Citation
Se. Handfieldjones et al., THE ANTICONVULSANT HYPERSENSITIVITY SYNDROME, British journal of dermatology, 129(2), 1993, pp. 175-177
Citations number
7
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
British journal of dermatology → ACNP
ISSN journal
00070963
Volume
129
Issue
2
Year of publication
1993
Pages
175 - 177
Database
ISI
SICI code
0007-0963(1993)129:2<175:TAHS>2.0.ZU;2-U
Abstract
Anticonvulsants can cause a characteristic hypersensitivity reaction. This multisystem reaction typically presents as fever, mucocutaneous e ruptions, lymphadenopathy and hepatitis. There is cross-reactivity bet ween different anticonvulsants, which complicates subsequent therapy. We report three cases to illustrate both the typical features, and les s common complications, of this under-recognized and life-threatening syndrome.