Aj. Ritchie et al., CARDIAC DYSRHYTHMIA IN TOTAL THORACIC ESOPHAGECTOMY - A PROSPECTIVE-STUDY, European journal of cardio-thoracic surgery, 7(8), 1993, pp. 420-422
A prospective controlled randomized clinical study of 50 patients unde
rgoing total thoracic oesophagectomy by one surgical team is described
, in which one group of patients was given prophylactic digoxin and th
e other was not. The incidence of cardiac dysrhythmia in each group wa
s compared. Fourteen (56%) of 25 patients digitalized, compared to 16
(64%) of 25 patients not digitalized, suffered cardiac dysrhythmia, wi
th a total incidence of 30 patients (60%). The first onset of dysrhyth
mia occurred within 48 h in 89% of the patients who suffered this comp
lication. These results indicate a high incidence of cardiac dysrhythm
ia in patients undergoing this operative procedure, which is not signi
ficantly reduced by prophylactic digitalization and which is likely to
occur within 2 days of surgery.