Blockade of conduction in the saphenous nerve is important in providin
g surgical anaesthesia in the lower leg. Unfortunately, previously des
cribed techniques have lacked clinical effectiveness in practice. We d
eveloped a transsartorial approach for conduction block of the sapheno
us nerve. We first confirmed its potential clinical utility in 12 cada
veric specimens by demonstrating that the saphenous nerve was consiste
ntly stained by injections of methylene blue. Subsequently, we compare
d the relative rates of successful saphenous nerve block and the exten
t of conduction block provided by three techniques: (1) transsartorial
saphenous nerve block (TSSNB), (2) above knee femoral paracondylar fi
eld block (FPFB), and (3) below knee field block (BKFB) of the sapheno
us nerve in 20 ASA I volunteers. The transsartorial saphenous nerve bl
ock proved to be highly successful (80% success rate) and was superior
to the other two approaches in providing cutaneous analgesia to pinpr
ick in the saphenous nerve distribution (P < 0.05). The success rates
of the BKFB and FPFB were 65% and 40% respectively. A successful block
with the transsartorial approach provided complete anaesthesia of the
medial malleolus in 94% of subjects whilst the BKFB and FPFB provided
complete anaesthesia of the medial malleolus in less than 40% of the
successful blocks We recommend the transsartorial approach for more ef
fective block of the saphenous nerve.