Objectives: To describe Australian-born women's experience of symptoms
during the natural menopause transition and the relative contribution
of menopausal and health status, social factors and lifestyle behavio
urs. Design: A community based cross-sectional survey by telephone int
erview was carried out on a randomly derived sample of Melbourne women
. Participants: The participants were 2000 Australian-born women, aged
between 45 and 55 years. Outcome measures: A list of 22 symptoms was
used. Explanatory variables were: sociodemographic variables; menopaus
al and health status; lifestyle behaviours; attitudes to ageing and to
menopause. Results: A 70% response rate was achieved for eligible wom
en who could be contacted during the study. Premenopausal women were t
he least symptomatic and perimenopausal women the most symptomatic. Fa
ctor analysis found seven common factors from the 22 symptoms studied.
Menopausal status based on menstrual history was significantly relate
d to two groups of symptoms: vasomotor symptoms, which increased throu
gh the menopausal transition; and general somatic symptoms which were
more frequent in the perimenopause. Analysis of variance of factor sco
res found fewer symptoms with increasing years of education, better se
lf-rated health, the use of fewer non-prescription medications, the ab
sence of chronic health conditions, a low level of interpersonal stres
s, the absence of premenstrual complaints, not currently smoking, exer
cise at least once a week, and positive attitudes to ageing and menopa
use. Conclusions: Many factors unrelated to hormonal changes contribut
ed to the symptoms. Longitudinal investigation is needed to determine
the relative importance of hormonal, psychosocial and lifestyle variab
les in the aetiology of mid-life symptoms.