The proper design of a left ventricular assist device (LVAD) requires
an understanding of the pump's fluid dynamic and biocompatible propert
ies. A hydraulically efficient system minimizes the power required for
pumping. Biocompatibility refers to the ability to pump blood with mi
nimal hemolysis and thrombus formation. Typically, shear stresses belo
w a threshold level will not damage blood significantly. A fluid dynam
ic analysis of a prototype centrifugal pump designed for use as an LVA
D was performed to establish flow characteristics. A flow visualizatio
n technique using Amberlite particles suspended in a glycerin/water bl
ood analogue was used. The system was illuminated with a 1 mm planar b
eam strobed helium-neon laser, and the results were recorded photograp
hically. An analysis of photographs revealed laminar and turbulent flo
ws with vortices within an illuminated plane in both the inlet and out
let port areas. From these data, velocity and shear stress profiles we
re generated that showed possible areas of improvement. It was conclud
ed that the outlet port design could be improved by changing its angle
and the continuity of its expansion. The inlet port could also be imp
roved by smoothing the transition area between the inlet tube and the
pump body to allow for gradual acceleration of the entering fluid.