Covered maze traversal models nonverbal planning, involving sequential
execution of moves using learned spatial maps. To determine the neura
l substrate involved in maze processing, eleven adults underwent [(H2O
)-O-15]-PET while performing motor control, following the computer; vi
sual control, choosing the wall with more dead-ends; uncovered maze, t
raversing fully visible mazes; covered maze, traversing mazes only loc
ally visible. Maze processing lateralizes to the right hemisphere: unc
overed maze versus controls revealed area 23 and 29 activation; covere
d maze versus controls activated areas 8, 10 and 19. The extrastriate
region may store path information, evoked by prefrontal areas for spat
ial planning and navigation. Published by Elsevier Science Ltd.