T. Westermarck et al., SELENIUM SUPPLEMENTATION AND TRACE-ELEMENT ALTERATIONS IN DOWNS-SYNDROME, Journal of trace elements and electrolytes in health and disease, 7(2), 1993, pp. 125-126
Long-term selenium supplementation (0.015-0.025 mg/kg per day) in the
form of sodium selenite decreased by 50% the elevated mononuclear cell
copper content in Down's syndrome persons. The iron and copper levels
were higher, and the zinc level was lower in the DS-groups than in th
e control group, however, the transition metal copper level was partic
ularly high in the Se-unsupplemented DS-group.