Mj. Hicks et al., SUBCUTANEOUS FAT NECROSIS OF THE NEWBORN AND HYPERCALCEMIA - CASE-REPORT AND REVIEW OF THE LITERATURE, Pediatric dermatology, 10(3), 1993, pp. 271-276
Subcutaneous fat necrosis of the newborn (SCFN) alone is an uncommon c
ondition. Its association with hypercalcemia has been reported in 19 n
eonates since 1926. The two occur in full-term to postterm newborns wi
th perinatal complications associated with delivery. Erythematous to v
iolaceous, firm, subcutaneous nodules appear approximately 1 to 4 week
s after delivery, preceding the development of signs and symptoms of h
ypercalcemia. Although SCFN and hypercalcemia are rare complications i
n neonates with perinatal problems, death due to the sequelae of hyper
calcemia occurred in 3 of the 19 patients. A neonate who develops skin
lesions consistent with SCFN should be followed for possible onset of
hypercalcemia and treated in a timely fashion.