A. Cerdanvidal et al., INTERSECTION POINT METHOD (IPM) - THEORETICAL BASIS AND APPLICATION TO SPECTROPHOTOMETRIC ANALYSES, Fresenius' journal of analytical chemistry, 357(6), 1997, pp. 572-576
The Intersection Point Method (IPM) is a new method for the determinat
ion of an analyte in the presence of several unknown interferences. Th
e method is based on the Apparent Content Curves (ACC) from derivative
signals. To test the proposed procedure an analysis of mixtures of in
dicators with strong spectral overlapping was carried out. Results obt
ained agree with the theoretical values. Besides, the determination of
caffeine in several pharmaceuticals by IPM provides good results.