CONGENITAL BILATERAL JUVENILE GRANULOSA-CELL TUMOR OF THE OVARY IN LEPRECHAUNISM - A CASE-REPORT

Authors
BRISIGOTTI M FABBRETTI G PESCE F GATTI R COHEN A PARENTI G CALLEA F
Citation
M. Brisigotti et al., CONGENITAL BILATERAL JUVENILE GRANULOSA-CELL TUMOR OF THE OVARY IN LEPRECHAUNISM - A CASE-REPORT, Pediatric pathology, 13(5), 1993, pp. 549-558
Citations number
21
Categorie Soggetti
Pathology,Pediatrics
Journal title
Pediatric pathology → ACNP
ISSN journal
02770938
Volume
13
Issue
5
Year of publication
1993
Pages
549 - 558
Database
ISI
SICI code
0277-0938(1993)13:5<549:CBJGTO>2.0.ZU;2-5
Abstract
We report on a case of leprechaunism. In addition to the typical clini cal and biochemical features, a bilateral juvenile granulosa cell tumo r of the ovaries and cytomegalovirus hepatitis were found. The granulo sa cell tumor may result from the mitogenic effect of insulin at high concentration, which acts via a mechanism mediated by insulin-like gro wth factor I receptors.