PREPARATION OF HEAT RESPONDING ARTIFICIAL CELLS

Authors
MURAMATSU N NAGAHAMA T KONDO T
Citation
N. Muramatsu et al., PREPARATION OF HEAT RESPONDING ARTIFICIAL CELLS, Biomaterials, artificial cells, and immobilization biotechnology, 21(4), 1993, pp. 527-536
Citations number
29
Categorie Soggetti
Engineering, Biomedical","Material Science
Journal title
Biomaterials, artificial cells, and immobilization biotechnology → ACNP
ISSN journal
10557172
Volume
21
Issue
4
Year of publication
1993
Pages
527 - 536
Database
ISI
SICI code
1055-7172(1993)21:4<527:POHRAC>2.0.ZU;2-G
Abstract
Enzyme-loaded microcapsules were prepared and treated with dimyristoyl phosphatidylcholine molecules so as to control the permeation of subst rates through the microcapsule membranes. The activities of enclosed e nzymes increased with increase in ambient temperature, but gave an abr upt change at around the phase transition temperature of the lipid. Th e experimental results indicaca the possibility of making artificial c ells which respond to the temperature change of the surrounding medium .