APOPROTEIN-B IN SUBRETINAL FLUID

We studied the presence of apolipoprotein B (apo B) by immunoelectroph oresis in subretinal fluid (SRF) and serum from 15 rhegmatogenous reti nal detachments and 5 retinal detachments with proliferative vitreoret inopathy (PVR). Apo B concentration +/- standard deviation was 1.49 +/ - 1.06 mg/dl in SRF and 108.41 +/- 40.22 mg/dl in serum. Only in four cases was apo B not detected in SRF. We found no significant correlati on between apo B concentrations in SRF and apo B levels in serum. We d id not find a positive correlation between apo B concentrations in SRF and the duration and size of the detachments. There was no statistica l relationship between the presence of PVR and apo B levels. This phen omenon suggests the preservation of the outer blood retinal barrier du ring rhegmatogenous retinal detachment.