In this study, we attempted to compare food motivation in Brown-Norway
rats of three different ages (8, 14, and 26 months old) under two dif
ferent levels of food deprivation by measuring running speed in a runw
ay. Food motivation was also assessed in a progressive ratio schedule
of reinforcement in an operant chamber at one level of deprivation. Co
mpared with the adult and middle-aged rats, the old rats had a slower
running speed in the runway and made fewer leverpresses in the progres
sive ratio test. It was suggested that both age and weight affected th
e level of food motivation. A differential food deprivation technique
(i.e., an age-related increase in the percentage of body weight reduct
ion) may possibly be a way to reduce differences in levels of food mot
ivation in rats of different ages.