THE HUMAN D11S554 LOCUS - 4 DISTINCT FAMILIES OF REPEAT PATTERN ALLELES AT ONE LOCUS

Authors
ADAMS M URQUHART A KIMPTON C GILL P
Citation
M. Adams et al., THE HUMAN D11S554 LOCUS - 4 DISTINCT FAMILIES OF REPEAT PATTERN ALLELES AT ONE LOCUS, Human molecular genetics, 2(9), 1993, pp. 1373-1376
Citations number
14
Categorie Soggetti
Genetics & Heredity",Biology
Journal title
Human molecular genetics → ACNP
ISSN journal
09646906
Volume
2
Issue
9
Year of publication
1993
Pages
1373 - 1376
Database
ISI
SICI code
0964-6906(1993)2:9<1373:THDL-4>2.0.ZU;2-3
Abstract
We have sequenced amplified products of 44 short tandem repeat alleles at the human D11S554 locus. The sequences revealed four distinct, but related, families of consensus repeat patterns. Six alleles deviated from the consensus patterns. Alleles differed in size by as little as one base pair, and precise sizing is required for analysis of alleles at this highly polymorphic locus. The evolution of alleles at the D11S 554 locus and related short tandem repeat loci is discussed.