Background-Palliative treatments for obstruction of the superior vena
cava all have disadvantages. The use of a fine braided wire self expan
ding stent (Wallstent, Schneider (Europe) AG) in patients with maligna
nt and benign causes of superior vena cava obstruction is reported. Me
thods-Five patients with obstruction of the superior vena cava were tr
eated with balloon angioplasty of the stricture and the percutaneous i
nsertion of an expandable Wallstent endoprosthesis across the site of
the stricture. Four patients had advanced mediastinal malignancy previ
ously treated by radiotherapy and one patient had fibrosing mediastini
tis. Results-All patients experienced rapid symptomatic relief and, in
three cases, complete palliation was achieved during survival times o
f seven weeks, nine weeks, and 24 weeks, respectively. Two surviving p
atients (with a recurrent thymoma and fibrosing mediastinitis) were fr
ee of symptoms when followed up at eight and nine months respectively.
Conclusions-Initial experience with the Wallstent endoprosthesis sugg
ests that it is a valuable treatment alternative once conventional the
rapy has failed and gives rapid relief of symptoms to patients with ob
struction of the superior vena cava.