R. Noyes et al., ENVIRONMENTAL-FACTORS RELATED TO THE OUTCOME OF PANIC DISORDER - A 7-YEAR FOLLOW-UP-STUDY, The Journal of nervous and mental disease, 181(9), 1993, pp. 529-538
The purpose of this study was to examine factors related to the outcom
e of naturalistically treated panic disorder. In order to achieve this
we followed up 69 patients 7 years after they had presented at a psyc
hiatric clinic. At follow-up, the patients were generally doing well d
espite persisting symptoms. Patients who were more severely ill at the
time of initial assessment had a worse outcome. These patients had mo
re severe panic and agoraphobic symptoms, had illnesses of longer dura
tion, and more often had histories of major depression. Among the deve
lopmental variables examined, separation from a parent by death or div
orce was strongly related to poor outcome. Other factors associated wi
th poor outcome included high interpersonal sensitivity, low social cl
ass, and unmarried marital status. The findings show that, for this ch
ronic illness, measures of severity and chronicity predict more severe
and persisting symptoms. They also indicate that outcome is important
ly related to the social environment in which the illness develops and
with which it interacts.