TUMOR-CONTROL PROBABILITY FOR PERMANENT IMPLANTS IN PROSTATE

The tumor control probabilities (TCPs) for 11 transperineal permanent implants of the prostate With I-125 seeds have been computed, based on target-specific volume-dose histogram data. Prostate dose-response of this modality is converted from that of external beam therapy based o n biologically effective dose derived from the alpha/beta model. The c alculated TCPs for these transperineal prostate cases are compared wit h the results of 679 previous retropubic implants, providing interesti ng insight about these two techniques. Further refinement and validati on of this model await long-term followup results of sufficient number of patients.