IMMUNOHISTOCHEMICAL DEMONSTRATION OF NEURON-SPECIFIC ANTIGEN, HPC-1 IN THE ENTERIC NERVOUS-SYSTEM OF THE GUINEA-PIG DISTAL COLON

Authors
NAGAHAMA M TSUTSUI Y KUWAHARA A AKAGAWA K
Citation
M. Nagahama et al., IMMUNOHISTOCHEMICAL DEMONSTRATION OF NEURON-SPECIFIC ANTIGEN, HPC-1 IN THE ENTERIC NERVOUS-SYSTEM OF THE GUINEA-PIG DISTAL COLON, Neuroscience letters, 160(1), 1993, pp. 37-40
Citations number
15
Categorie Soggetti
Neurosciences
Journal title
Neuroscience letters → ACNP
ISSN journal
03043940
Volume
160
Issue
1
Year of publication
1993
Pages
37 - 40
Database
ISI
SICI code
0304-3940(1993)160:1<37:IDONAH>2.0.ZU;2-L
Abstract
The HPC-1 antigen is a newly identified neuron specific membrane prote in in the central nervous system. The HPC-1 antigen was revealed simil arity to epimorphin. The presence of HPC-1 antigen in the enteric nerv ous system of guinea-pig distal colon was immunohistochemically demons trated using the antibody against the HPC-1. Immunohistochemical study clearly revealed the topography and structure of the enteric nervous system of the guinea-pig distal colon. HPC-1 was present only in the n ervous system and entirely distributed. HPC-1 antigen is present at th e surfaces of ganglion cells, but not in the cytoplasm.