Two 'imported' cases of relapsing fever after a trip through Senegal a
re described. Two women developed a tick-borne relapsing fever after h
aving slept outdoors on a terrace in Zinguichor, Senegal. The first pa
tient was rapidly cured after a course of doxycycline. The second pati
ent initially received erythromycin, but despite this treatment she de
veloped neurological symptoms and Borrelia persisted in the thick-smea
r examination. After treatment with doxycycline she developed a Jarish
-Herxheimer reaction. Treatment with doxycycline was continued and fin
ally all symptoms disappeared within 36 hours after starting this trea
tment. A diagnosis of relapsing fever should be considered in all pati
ents returning from the tropics with recurrent fever, especially if no
malaria parasites are found.