In chronic radiation proctitis bleeding occurs from mucosal friability
and neovascular telangiectasias. Fourteen patients with bleeding from
chronic radiation proctitis underwent endoscopic argon laser therapy
at 4 to 8 W. The goal of treatment was obliteration of all telangiecta
sias. The average follow-up was 35 months. Of the 51 procedures, 48 (9
4%) were performed on outpatients with enema preparation and little or
no sedation. A median of three procedures was performed per patient,
with two sessions required for initial control of bleeding. Ten patien
ts (71%) required maintenance therapy for recurrent bleeding from tela
ngiectasias that developed after initial therapy. The mean interval be
tween maintenance sessions was 7 months. No immediate or late complica
tions occurred.