A PROSPECTIVE-STUDY OF CHLORAMPHENICOL INDUCED APLASTIC-ANEMIA IN NIGERIANS

Authors
DUROSINMI MA AJAYI AA
Citation
Ma. Durosinmi et Aa. Ajayi, A PROSPECTIVE-STUDY OF CHLORAMPHENICOL INDUCED APLASTIC-ANEMIA IN NIGERIANS, Tropical and geographical medicine, 45(4), 1993, pp. 159-161
Citations number
9
Categorie Soggetti
Tropical Medicine","Public, Environmental & Occupation Heath
Journal title
Tropical and geographical medicine → ACNP
ISSN journal
00413232
Volume
45
Issue
4
Year of publication
1993
Pages
159 - 161
Database
ISI
SICI code
0041-3232(1993)45:4<159:APOCIA>2.0.ZU;2-A
Abstract
A five-year prospective study of chloramphenicol induced aplastic anae mia in Nigerians was undertaken. Five proven cases were seen, represen ting 45.5% of all cases of aplastic anaemia diagnosed during the perio d of study and 1.0 cases per year. Chloramphenicol induced aplastic an aemia is rare (only 0.002% of all new non-obstetric patients seen in t he hospital during the Period of study) but preventable. Restriction o f the drug or its total withdrawal is recommended.