A 26-year-old male presented with oedema, massive albuminuria and micr
oscopic haematuria. Kidney biopsy revealed enlarged cellular glomeruli
infiltrated by polymorphs and eosinophils with focal fibrin deposits
along the basement membrane. Microfilariae were seen in the lumen of f
ew glomerular capillaries. Antistreptolysin titre was negative.The abs
ence of other aetiological factors and presence of microfilariae withi
n glomeruli suggests that nephrotic syndrome may be due to a filarial
nephritis.