Thirty-five consecutive patients underwent en bloc resection of cardia
cancer without thoracotomy. All tumors were adenocarcinoma. The opera
tive procedure involved wide resection of the peri-hiatal diaphragm, d
issection of the upper abdominal and lower mediastinal lymph nodes, an
d resection of the stomach including a portion of the lower thoracic e
sophagus without thoracotomy. The resection area of the diaphragm incl
uded not only the crural muscle as in other methods, but also the diap
hragmatic tissue surrounding the esophageal hiatus. Through the enlarg
ed hiatus, dissection of the mediastinum was possible up to the carina
from the abdominal cavity. The mediastinal node stations were affecte
d in 25% of patients whose tumor invaded to the serosa. Hypotension wi
th or without atrial arrythmias and pleural tears occurred during surg
ery in 20 patients (57%) and in 18 patients (51%), respectively. Posto
peratively, hypoxia requiring reintubation developed in 7 patients (19
%), pleural effusions needed tube drainage in 16 patients (46%), atele
ctasis in 5 patients (14%), and anastomotic leaks in 3 patients (9%).
They were all successfully treated. The cumulative 5-year survival rat
e for 21 patients with stages I (2 patients), II (9), and III (10) dis
eases was 62%, whereas none of the patients with stage IV disease live
d for more than 2 years after surgery. Because thoracotomy is avoided,
the procedure is better tolerated by debilitated patients. We believe
this technique is a reasonable and safe alternative to the left thora
cotomy approach for resection of cancer of the gastric cardia. (C) 199
3 Wiley-Liss, Inc.