Sleep disorders are common in midlife and older adults, coinciding wit
h encephalographic changes in sleep patterns, stressful life events, a
nd chronic diseases of aging. Differential diagnosis includes respirat
ory abnormalities (including obstructive sleep apnea), leg cramps, noc
turia, ulcer-related pain, medication use, depression, and anxiety. Se
dative-hypnotic agents may be appropriate for selected patients, with
short-acting substances preferred in all cases. Dosage and dosing sche
dules should be discussed with the patient to ensure compliance and to
avoid possible misuse of these agents.