A. Zennyoji et al., INCREASED RAHA TITER AND INTERLEUKIN-6 LEVELS IN THE SYNOVIAL-FLUID IN A PATIENT WITH POLYMYALGIA-RHEUMATICA, Internal medicine, 32(6), 1993, pp. 484-486
We report a patient with polymyalgia rheumatica (PMR) accompanied by a
n increased Rheumatoid Arthritis Hemagglutinin Test (RAHA) titer and i
nterleukin-6 level in the synovial fluid. A 60-year-old female was adm
itted because of polymyalgia, a body temperature of 39.2-degrees-C, an
d an erythrocyte sedimentation rate increased to 94 mm/h. Since a musc
le biopsy failed to show a specific finding, she was diagnosed as PMR.
The titer of RAHA and the interleukin-6 level were increased only in
the synovial fluid; prednisolone treatment decreased both. The present
case raised the possibility that a similar mechanism in rheumatoid ar
thritis may involve the development of synovitis in PMR.