Sa. Lee et al., MULTIPLE EXCITATION COLLISIONAL ACTIVATION IN FOURIER-TRANSFORM MASS-SPECTROMETRY, Rapid communications in mass spectrometry, 7(9), 1993, pp. 819-821
Multiple excitation collisional activation (MECA) has been examined us
ing Fourier-transform mass spectrometry. In analogy to recently report
ed multiple excitation detection schemes, MECA is a process in which i
ons are translationally excited to larger orbits by applying an RF sig
nal over the desired mass range. Next, collisional cooling of the ions
collapses them, spatially, back to the center of the cell, where the
process can be repeated. Two examples of the utility of MECA are given
. The first involves a novel way of growing cluster ions by sequential
ion/molecule reactions followed by MECA. The second uses MECA to incr
ease the energy deposition in a stable and difficult-to-fragment ion,
thereby inducing fragmentation.