SEGMENTAL ANHIDROSIS IN THE SPINAL DERMATOMES IN SJOGRENS SYNDROME-ASSOCIATED NEUROPATHY

We describe two women with primary Sjogren's syndrome and sensory neur opathy who had anhidrosis segmentally along the dermatomes of the spin al segment, along with sensory loss. Intradermal administration of cho linergic agents elicited no sweat response in the spinal segments with anhidrosis, whereas a normal response was present in the segments wit h obvious sweating. These features suggest segmental involvement of th e postganglionic sympathetic ganglion cells.