The dynamics of allele frequencies changing under migration and hetero
geneous selection in a subdivided population are investigated. Using p
erturbation techniques, a stationary state is obtained when migration
and selection are both small. Heterogeneous selection leads to a posit
ive correlation between values of F-statistics and heterozygosities wh
en these are compared among sets of subdivided populations. This contr
asts with a negative value of the correlation obtained under Wright's
classical model of homogeneous selection, and with the absence of corr
elation in the completely neutral situation.