THERMODYNAMICS OF SOLVATION IN MIXED-SOLVENTS

Chemists have long recognized that changes in solvent have profound ef fects on the properties of chemical systems. However it is only in the past quarter of a century that theoretical models which will predict these effects have emerged. This article outlines the development of o ne such model and shows how it provides detailed information about the roles of the interactions between solvent and solute molecules in det ermining the thermodynamics of chemical systems.