PURPOSE: To determine whether computed tomographic (CT) angiography ca
n be used to accurately quantify carotid stenoses and differentiate se
vere stenoses from occlusions. MATERIALS AND METHODS: CT angiography w
as used to evaluate 50 carotid arteries in 27 patients who were referr
ed for surgical evaluation after diagnosis of carotid stenosis and who
had undergone standard angiography. Four observers read each study se
parately in a blinded fashion, then all four observers together review
ed those studies in which the individual readings differed to reach a
consensus reading. RESULTS: The consensus readings for the two modalit
ies were in agreement on stenosis category in 41 (82%) of the 50 carot
id arteries (kappa(w) = 0.852 +/- 0.114). The consensus readings in th
e other nine arteries differed by only one category; seven had less se
vere stenosis at CT angiography and two had more severe stenosis. The
CT angiograms also depicted a variety of additional abnormalities, inc
luding loops (n = 6), aneurysms (n = 2), and ulcers (n = 4). CONCLUSIO
N: These results indicate that CT angiography can non-invasively provi
de most of the information needed before carotid endarterectomy.