ULTRASTRUCTURAL MORPHOMETRIC INVESTIGATION OF THE HEART OF RABBITS AFTER A SINGLE ADMINISTRATION OF RESERPINE

Citation
G. Wassilew et al., ULTRASTRUCTURAL MORPHOMETRIC INVESTIGATION OF THE HEART OF RABBITS AFTER A SINGLE ADMINISTRATION OF RESERPINE, Experimental and toxicologic pathology, 45(4), 1993, pp. 217-222
Citations number
23
Categorie Soggetti
Pathology,Toxicology
ISSN journal
09402993
Volume
45
Issue
4
Year of publication
1993
Pages
217 - 222
Database
ISI
SICI code
0940-2993(1993)45:4<217:UMIOTH>2.0.ZU;2-E
Abstract
The ultrastructure of myocardial cells of chinchilla rabbits was morph ometrically examined after administration of one dose of reserpine. Th e results show that 24 hours after administration of reserpine, there is a decrease in the number and an increase in the size of the mitocho ndria, a relaxation or narrowing and ramification of myofibrils, an in crease in intracellular lipid content compared with control animals. T hese changes are the result of functional and chemical desympathizatio n and they represent an ultrastructural-morphometric characteristic of the action on cardiomyocytes.