Jc. Gore et al., RADIATION-DOSE DISTRIBUTIONS IN 3 DIMENSIONS FROM TOMOGRAPHIC OPTICAL-DENSITY SCANNING OF POLYMER GELS .1. DEVELOPMENT OF AN OPTICAL SCANNER, Physics in medicine and biology, 41(12), 1996, pp. 2695-2704
A new method of dosimetry of ionizing radiations has been developed th
at makes use of tissue-equivalent polymer gels which are capable of re
cording three-dimensional dose distributions. The dosimetric data stor
ed within the gels are measured using optical tomographic densitometry
. The dose-response mechanism relies on the production of light scatte
ring microparticles which result from the polymerization of acrylic co
monomers dispersed in the gel. The attenuation of a collimated Light b
eam caused by scattering in the irradiated optically turbid medium is
directly related to the radiation dose over the range 0-10 Gy. An opti
cal scanner has been developed which incorporates an He-Ne laser, phot
odiode detectors, and a rotating gel platform. Using mirrors mounted o
n a translating stage, the laser beam scans across the gel between eac
h incremental rotation of the platform. Using the set of optical densi
ty projections obtained, a cross sectional image of the radiation fiel
d is then reconstructed. Doses in the range 0-10 Gy can be measured to
better than 5% accuracy with a spatial resolution approximate to 2 mm
using the current prototype scanner. This method can be used for the
determination of three-dimensional dose distributions in irradiated ge
ls, including measurements of the complex distributions produced by mu
lti-leaf collimators, dynamic wedge and stereotactic treatments, and f
or quality assurance procedures.