Ml. Lefevre et al., A RANDOMIZED TRIAL OF PRENATAL ULTRASONOGRAPHIC SCREENING - IMPACT ONMATERNAL MANAGEMENT AND OUTCOME, American journal of obstetrics and gynecology, 169(3), 1993, pp. 483-489
ObJECTIVES: This randomized clinical trial of 15,530 women was designe
d to test the hypothesis that screening ultrasonography in low-risk pr
egnancies would improve perinatal outcome. A secondary hypothesis addr
essed in this article was that screening ultrasonography would have a
favorable impact on maternal management or outcome. STUDY DESIGN: Preg
nant women without a specific indication for ultrasonographic examinat
ion in early pregnancy were randomly assigned to have either two scree
ning sonograms or conventional obstetric care. Pregnancy interventions
and maternal outcomes were compared in the two groups. RESULTS: No si
gnificant differences were found in maternal outcomes. Use of ultrason
ography was markedly higher in the screened group. The rates of induce
d abortion, amniocentesis, tests of fetal well-being, external version
, induction, and cesarean section and the distribution of total hospit
al days were similar in the two groups. Use of tocolytics and the rate
of postdate pregnancy were both slightly lower in the screened group.
CONCLUSION: Screening ultrasonography resulted in no clinically signi
ficant benefit.