UNUSUAL DEFICIENCY OF THE MODIFIED PURINE BASE QUEUINE IN TRANSFER-RIBONUCLEIC-ACID FROM THE HUMAN PLACENTA AS TESTED BY ENZYMATIC ASSAY

Authors
BARANOWSKI W TOMASZEWSKI J KEITH G
Citation
W. Baranowski et al., UNUSUAL DEFICIENCY OF THE MODIFIED PURINE BASE QUEUINE IN TRANSFER-RIBONUCLEIC-ACID FROM THE HUMAN PLACENTA AS TESTED BY ENZYMATIC ASSAY, American journal of obstetrics and gynecology, 169(3), 1993, pp. 581-582
Citations number
2
Categorie Soggetti
Obsetric & Gynecology
Journal title
American journal of obstetrics and gynecology → ACNP
ISSN journal
00029378
Volume
169
Issue
3
Year of publication
1993
Pages
581 - 582
Database
ISI
SICI code
0002-9378(1993)169:3<581:UDOTMP>2.0.ZU;2-6
Abstract
Transfer ribonucleic acid from rapidly growing tissues, particularly f rom neoplasia, is partially deficient in queuine, a highly modified tr ansfer ribonucleic acid constituent. By means of an enzymatic assay we also found a queuine deficiency (14%) in human placenta transfer ribo nucleic acid despite its high concentrations in the amniotic fluid. Pr oposed cause and significance of the results are discussed.