STRUCTURE AND DYNAMICS OF MOLECULAR MOTORS

Authors
AMOS LA CROSS RA
Citation
La. Amos et Ra. Cross, STRUCTURE AND DYNAMICS OF MOLECULAR MOTORS, Current opinion in structural biology, 7(2), 1997, pp. 239-246
Citations number
57
Categorie Soggetti
Cell Biology",Biology
Journal title
Current opinion in structural biology → ACNP
ISSN journal
0959440X
Volume
7
Issue
2
Year of publication
1997
Pages
239 - 246
Database
ISI
SICI code
0959-440X(1997)7:2<239:SADOMM>2.0.ZU;2-K
Abstract
The structures of the oppositely directed microtubule motors kinesin a nd ncd have been solved to atomic resolution. The two structures are v ery similar and are also homologous to myosin. Myosins and kinesins di ffer kinetically but, tantalizingly, cryoelectron microscopy has recen tly revealed that both structures may tilt during ADP release. Such ev idence suggests that the two motor families use common structural mech anisms.