CYTOMEGALOVIRUS ANTIGENEMIA - CLINICAL CORRELATIONS IN TRANSPLANT RECIPIENTS AND IN PERSONS WITH AIDS

Authors
MAZZULLI T RUBIN RH FERRARO MJ DAQUILA RT DOVEIKIS SA SMITH BR THE TH HIRSCH MS
Citation
T. Mazzulli et al., CYTOMEGALOVIRUS ANTIGENEMIA - CLINICAL CORRELATIONS IN TRANSPLANT RECIPIENTS AND IN PERSONS WITH AIDS, Journal of clinical microbiology, 31(10), 1993, pp. 2824-2827
Citations number
23
Categorie Soggetti
Microbiology
Journal title
Journal of clinical microbiology → ACNP
ISSN journal
00951137
Volume
31
Issue
10
Year of publication
1993
Pages
2824 - 2827
Database
ISI
SICI code
0095-1137(1993)31:10<2824:CA-CCI>2.0.ZU;2-H
Abstract
We evaluated a rapid immunoperoxidase technique for the detection of c ytomegalovirus (CMV) antigenemia in peripheral blood neutrophils of 56 transplant recipients (117 specimens) and 36 persons with AIDS (59 sp ecimens). Antigenemia was 92% sensitive and 98% specific for the detec tion of clinical CMV infection in transplant recipients and 100% sensi tive and 86% specific in persons with AIDS. Overall, CMV antigenemia w as a more rapid and sensitive method for the detection of clinical CMV infection than either shell vial culture or conventional tube culture of blood.