Ct. Supuran et al., REACTION OF PYRYLIUM-SALTS WITH AMINO-ACID DERIVATIVES .2. PREPARATION OF AMINOGLUTETHIMIDE DERIVATIVES, Revue Roumaine de Chimie, 38(5), 1993, pp. 605-612
Reaction of 2-ethyl-2-(4-aminophenyl)-glutarimide (aminoglutethimide)
with 2 4,6-tri- and 2,3,5,6-tetra-substituted pyrylium salts afforded
the corresPonding pyridinium salts, which were characterized by chemic
al analysis, IR, electronic and H-1-NMR spectrometry. Diastereotopic e
ffects were evidenced in the H-1-NMR spectra of the new derivatives us
ing homonuclear shift correlations (COSY).