REACTION OF PYRYLIUM-SALTS WITH AMINO-ACID DERIVATIVES .2. PREPARATION OF AMINOGLUTETHIMIDE DERIVATIVES

Authors
SUPURAN CT STOICESCU D MAIOR O BALABAN AT
Citation
Ct. Supuran et al., REACTION OF PYRYLIUM-SALTS WITH AMINO-ACID DERIVATIVES .2. PREPARATION OF AMINOGLUTETHIMIDE DERIVATIVES, Revue Roumaine de Chimie, 38(5), 1993, pp. 605-612
Citations number
20
Categorie Soggetti
Chemistry
Journal title
Revue Roumaine de Chimie → ACNP
ISSN journal
00353930
Volume
38
Issue
5
Year of publication
1993
Pages
605 - 612
Database
ISI
SICI code
0035-3930(1993)38:5<605:ROPWAD>2.0.ZU;2-5
Abstract
Reaction of 2-ethyl-2-(4-aminophenyl)-glutarimide (aminoglutethimide) with 2 4,6-tri- and 2,3,5,6-tetra-substituted pyrylium salts afforded the corresPonding pyridinium salts, which were characterized by chemic al analysis, IR, electronic and H-1-NMR spectrometry. Diastereotopic e ffects were evidenced in the H-1-NMR spectra of the new derivatives us ing homonuclear shift correlations (COSY).