A syndrome of acute interstitial nephritis (AIN) and anterior uveitis
is described in two children and the literature is reviewed. These dis
orders appear to improve, in uncontrolled studies, with systemic and t
opical ophthalmic corticosteroid treatment. Although the renal and ocu
lar prognoses appear good, it is important to recognize that patients
with AIN are at risk for uveitis and if present, consultation with an
ophthalmologist is recommended.