SYNTHESIS OF (+ -)-CP-99,994 - A HIGHLY POTENT SUBSTANCE-P ANTAGONIST/

Authors
DESAI MC THADEIO PF LEFKOWITZ SL
Citation
Mc. Desai et al., SYNTHESIS OF (+ -)-CP-99,994 - A HIGHLY POTENT SUBSTANCE-P ANTAGONIST/, Tetrahedron letters, 34(37), 1993, pp. 5831-5834
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
37
Year of publication
1993
Pages
5831 - 5834
Database
ISI
SICI code
0040-4039(1993)34:37<5831:SO(--A>2.0.ZU;2-A
Abstract
The synthesis of racemic CP-99,994, a highly potent substance P antago nist is reported. The synthesis outlined here is suitable for developi ng structure activity relationships for this important class of compou nds.