P. Knochel et al., A NEW CATALYTIC ASYMMETRIC APPROACH TO POLYFUNCTIONAL ALDOL PRODUCTS MEDIATED BY ZINC ORGANOMETALLICS, Tetrahedron letters, 34(37), 1993, pp. 5881-5884
The catalytic asymmetric addition of functionalized dialkylzincs to be
ta-alkoxyaldehydes provides after a short sequence of functional group
interconversions aldol products in 40-99% ee. Their stereoselective t
ransformation to either syn- or anti-1,3-diols has been performed.