A NEW CATALYTIC ASYMMETRIC APPROACH TO POLYFUNCTIONAL ALDOL PRODUCTS MEDIATED BY ZINC ORGANOMETALLICS

Authors
KNOCHEL P BRIEDEN W ROZEMA MJ EISENBERG C
Citation
P. Knochel et al., A NEW CATALYTIC ASYMMETRIC APPROACH TO POLYFUNCTIONAL ALDOL PRODUCTS MEDIATED BY ZINC ORGANOMETALLICS, Tetrahedron letters, 34(37), 1993, pp. 5881-5884
Citations number
66
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
37
Year of publication
1993
Pages
5881 - 5884
Database
ISI
SICI code
0040-4039(1993)34:37<5881:ANCAAT>2.0.ZU;2-D
Abstract
The catalytic asymmetric addition of functionalized dialkylzincs to be ta-alkoxyaldehydes provides after a short sequence of functional group interconversions aldol products in 40-99% ee. Their stereoselective t ransformation to either syn- or anti-1,3-diols has been performed.