Jm. Fabre et al., COLORECTAL-CARCINOMA IN PATIENTS AGED 75-YEARS AND MORE - FACTORS INFLUENCING SHORT AND LONG-TERM OPERATIVE MORTALITY, International surgery, 78(3), 1993, pp. 200-203
A review of 238 patients aged over 75 years and operated on for colore
ctal cancer was undertaken to analyse factors influencing short and lo
ng-term operative mortality. Operative mortality in the first postoper
ative month was 13% (n = 31) and 17% (n = 35) in the first year. Four
factors influenced significantly postoperative mortality in the first
month: postoperative complications (p = 0.0001) related to medical com
plications (p = 0.0001), emergency surgery (p = 0.007), type of anesth
esia (p = 0.01). Mortality during the first year (excluding patients w
ho died in the first month) was higher in females (p = 0.05), in patie
nts subjected lo emergency operation (p = 0.004), in patients with pre
existing, cerebrovascular accident (p = 0.04) and in patients with Duk
es C staging (p = 0.0001). A multivariate analysis with Cox's model re
vealed 3 prognostic factors: Dukes staging (p = 0.0001), medical compl
ications in the postoperative period (p = 0.0001) and type of anesthes
ia (p = 0.0009). Age as an isolated factor is not a contraindication t
o colorectal surgery in elderly patients presenting colonic or rectal
carcinoma. Prognosis in elderly patients is first correlated to the co
ntrol of postoperative mortality undergoing until the first year and t
hen to the cancer itself.