MALIGNANT-LYMPHOMA OF WALDEYER RING - A HISTOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY

The histopathological and immunohistological features of non-Hodgkin's lymphoma limited to the Waldeyer's ring were studied in 22 Japanese p atients using a panel of T- and B-cell markers on paraffin-embedded se ctions. All cases showed a diffuse growth pattern. Twenty cases were B -cell lymphomas and two were T-cell lymphomas. In contrast to the prim ary malignant lymphomas of the nasal cavity and paranasal sinuses, in which T-cell neoplasms are more frequently seen, the majority of the p rimary Waldeyer's ring lymphomas were B-cell neoplasms. Sixteen of the 20 cases of B-cell lymphoma were centroblastic lymphomas, and the mon omorphic variant comprised the majority of these; the other three B-ce ll lymphomas were immunocytomas. Two of the T-cell lymphomas showed mo rphological features of angiocentric lymphomas.