Sm. Mirsalimi et al., EFFECT OF HYPOBARIC HYPOXIA ON SLOW-GROWING AND FAST-GROWING CHICKENSFED DIETS WITH HIGH AND LOW-PROTEIN LEVELS, Avian diseases, 37(3), 1993, pp. 660-667
The occurrence of pulmonary hypertension syndrome in fast-growing broi
ler chickens and slow-growing leghorns was studied. In two similar tri
als, broiler chickens and white leghorns were placed either at low alt
itude (295 m) or in hypobaric chambers (simulated high altitude of 205
4 m) and fed either a high- (22%) or low-protein (17%) ration. Right v
entricular hypertrophy as measured by right-ventricle: total-ventricle
(RV:TV) weight ratio was used as an indicator of pulmonary hypertensi
on. The leghorns did not develop pulmonary hypertension as the result
of polycythemia induced by simulated high altitude. Compared with low-
altitude broilers and leghorns, broilers reared at high altitude respo
nded with significantly higher hematological values and 56% ascites mo
rtality because of right ventricular failure from pulmonary hypertensi
on, as measured by an increased RV:TV ratio.