Human chorionic gonadotropin and gonadotropin-releasing hormone admini
stration has been advocated for the nonoperative management of undesce
nded testes. Proponents of hormonal manipulation cite the low morbidit
y of endocrine treatment as its major advantage over conventional surg
ical repair. We report a serious potential complication of human chori
onic gonadotropin administration, intravaginal spermatic cord torsion
and testicular infarction, in an infant with bilateral cryptorchidism.