MORPHINE AS A CUE IN ASSOCIATIVE TOLERANCE TO MORPHINES ANALGESIC EFFECTS

Authors
CEPEDABENITO A TIFFANY ST
Citation
A. Cepedabenito et St. Tiffany, MORPHINE AS A CUE IN ASSOCIATIVE TOLERANCE TO MORPHINES ANALGESIC EFFECTS, Pharmacology, biochemistry and behavior, 46(1), 1993, pp. 149-152
Citations number
19
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Pharmacology, biochemistry and behavior → ACNP
ISSN journal
00913057
Volume
46
Issue
1
Year of publication
1993
Pages
149 - 152
Database
ISI
SICI code
0091-3057(1993)46:1<149:MAACIA>2.0.ZU;2-B
Abstract
This study examined the extent to which low doses of morphine paired e xplicitly with high doses would gain associative control over toleranc e development in rats. Tolerance development was assessed by evaluatin g dose-response curves to the analgesic effects of morphine on the tai l-flick test. The results indicated that tolerance development was not influenced by the pairing of low doses with high doses.