Opines consititute a class of substances that are characteristic of cr
own gall and hairy root, two proliferative plant diseases caused by Ag
robacterium tumefaciens and A. rhizogenes. About 20 of these compounds
have been described. Being produced by plant cells and used by the pa
thogen as growth substrates, they can be described as chemical mediato
rs of parasitism. This plant-bacteria interaction is a natural instanc
e of genetic manipulation since the genes encoding opine synthesis in
plant cells are transferred from a bacterial plasmid into the plant ge
nome. The current knowledge on opines is presented, as well as some bi
ological aspects of this unique system.