SYNTHESIS OF 4-AMINO-8-CYANOQUINAZOLINES FROM ENONES AND ENALS

Authors
VICTORY P BORRELL JI VIDALFERRAN A MONTENEGRO E JIMENO ML
Citation
P. Victory et al., SYNTHESIS OF 4-AMINO-8-CYANOQUINAZOLINES FROM ENONES AND ENALS, Heterocycles, 36(10), 1993, pp. 2273-2280
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
36
Issue
10
Year of publication
1993
Pages
2273 - 2280
Database
ISI
SICI code
0385-5414(1993)36:10<2273:SO4FEA>2.0.ZU;2-E
Abstract
The treatment in a sodium methoxide/methanol solution of alpha,beta-un saturated enones or aldehydes with propanedinitrile in a 1:2 molar rat io led to 2-aminobenzene-1,3-dicarbonitriles. These compounds afforded 4-amino-8-cyanoquinazolines by reaction with formamide or guanidine.