SYNTHESIS AND SEROTONERGIC ACTIVITY OF METHYLAMINO)BUTYL]-8-AZASPIRO[4.5]DECANE-7,9-DIONE

Citation
A. Benarab et G. Guillaumet, SYNTHESIS AND SEROTONERGIC ACTIVITY OF METHYLAMINO)BUTYL]-8-AZASPIRO[4.5]DECANE-7,9-DIONE, Heterocycles, 36(10), 1993, pp. 2327-2333
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
03855414
Volume
36
Issue
10
Year of publication
1993
Pages
2327 - 2333
Database
ISI
SICI code
0385-5414(1993)36:10<2327:SASAOM>2.0.ZU;2-B
Abstract
The synthesis of compound (9), a nitrogen-containing bioisostere of th e 1,4-benzodioxane moiety of the MDL 72832, is detailed. This compound showed a moderate affinity for the 5-HT1A receptors.