STRUCTURE OF THE ASCIDIAN, HALOCYNTHIA-RORETZI, TROPONIN-C GENE

Citation
Hj. Yuasa et al., STRUCTURE OF THE ASCIDIAN, HALOCYNTHIA-RORETZI, TROPONIN-C GENE, Journal of Biochemistry, 121(4), 1997, pp. 671-676
Citations number
35
Categorie Soggetti
Biology
Journal title
ISSN journal
0021924X
Volume
121
Issue
4
Year of publication
1997
Pages
671 - 676
Database
ISI
SICI code
0021-924X(1997)121:4<671:SOTAHT>2.0.ZU;2-0
Abstract
Two distinct cDNAs encoding troponin C (TnC) isoforms were isolated fr om the ascidian, Halocynthia roretzi, One is expressed in adult body w all smooth muscle and heart muscle, and the other in larval striated m uscle, The H. rorezti gene is composed of 7 exons separated by B intro ns, and Southern blot analysis showed that TnC is a single copy gene p roduct. The two isoforms of TnC were derived through the alternative s plicing of the third exon.